Venerable Khandro Rinpoche is the daughter of His Holiness Mindrolling Trichen who is head of the Nyingma School of Tibetan Buddhism and one of the most renowned Tibetan Lamas currently alive today. Born into the Mindrolling lineage, which throughout its history has had many accomplished female masters, Khandro Tsering Paldrön was recognized at the age of two by His Holiness the 16th Karmapa as the re-incarnation of the Great Dakini of Tsurphu, Khandro Ugyen Tsomo, one of the most renowned female masters of her time. The present Khandro Rinpoche holds the lineages of both the Nyingma and Kagyu traditions.

Khandro Rinpoche has received teachings and transmissions from some of the most accomplished masters of the 20th century, including His Holiness the Dalai Lama, His Holiness Mindrolling Trichen, His Holiness Dilgo Khyentse Rinpoche, His Eminence Trulzhig Rinpoche, His Eminance Tenga Rinpoche, His Eminance Tsetrul Rinpoche and His Eminance Tullku Ugyen Rinpoche.

Rinpoche maintains a rigorous schedule, teaching from both the Kagyu and Nyingma tradtions in the USA including Hawaii, Canada, Denmark, Norway, Spain, Germany, France, the Czech Republic and Greece. She has established and heads the Samten Tse Retreat Center in Mussoori, India, which is home to 30 nuns and also provides a place of study and retreat for monastics and western lay practitioners. Rinpoche is also Resident Teacher at the a Lotus Garden in rural Virginia, USA, which she established to provide retreat practice, the study of crucial Buddhist texts, and visiting teachers from all lineages. Rinpoche is also actively involved with the Mindrolling Monastery in Dehra Dun, India.